17º CONGRESSO BRASILEIRO DE NEUROLOGIA INFANTIL

Dados do Trabalho


Título

REDUCED FIDGETY MOVEMENTS IN CHILD PRENATALLY EXPOSED TO SARS-COV-2: A CASE REPORT

Apresentação do caso

A male baby born by Cesarean section at 37 weeks (APGAR 9/9), weighing 4280g, stature of 53 cm and cephalic perimeter of 38 cm. The 29 years-old mother (G5P4A1), previously hypertensive, had an active COVID-19 infection during childbirth. She had no other comorbidities. At four months, he presented with motor skills developmental delay, showcasing hypertonia of the lower limbs and axial hypotonia. Subsequently, he was submitted to various evaluations, such as the Hammersmith neurological evaluation, in which he achieved a score of 59 and as Alberta's Infant Motor Scale (scoring 12), attaining a percentile of 10. Finally, he underwent the General Movement Assessment (GMA), in which he presented abnormal fidgety movements, lack of foot-to-foot contact, and hand-to-hand contact, both expected at this age.

Discussão

The case under consideration refers to a child, prenatally exposed to the SARS-CoV-2 virus, who presented with motor skills dysfunction. Although many viral maternal infections are well associated with neurodevelopmental disorders, the effects of prenatal exposure to the COVID-19 virus on child development are still not well established. With this in mind, it is important to consider this type of infection's inflammatory potential, which can trigger maternal immune activation, mainly when associated with the inflammatory profile of the first and third semesters, and generate immunological responses strong enough to impair fetal development. In addition, the General Movement Assessment is a tool that evaluates possible early changes in neurodevelopment and it is already being used to describe abnormal fidgety movements of babies whose mothers had COVID-19 during their pregnancy. Based on the GMA results from the presented case, the child could be at risk for future neurological disorders.

Comentários finais

The consequences of prenatal exposure to the COVID-19 virus are not entirely known. Because of this, neurodevelopmental abnormalities observed in children submitted to these inflammatory conditions should be reported and investigated for further clarification.

Referências (se houver)

Fonte de Fomento (se houver)

Declaração de conflito de interesses de TODOS os autores

Não houveram conflitos de interesse

Área

Transtornos neuropsiquiátricos e distúrbios de aprendizagem

Instituições

Universidade Federal do Ceará - Ceará - Brasil

Autores

Isabelle Diniz Melo, Renata Castro Kehdi, Leticia Regia Lima Cavalcante, Deniele Bezerra Lós, Marylane da Silva Viana, Danielle Macêdo Gaspar