17º CONGRESSO BRASILEIRO DE NEUROLOGIA INFANTIL

Dados do Trabalho


Título

PREVALENCE OF INTELLECTUAL DISABILITY AS A COMORBIDITY OF AUTISM SPECTRUM DISORDER IN PATIENTS WITH MULTIDISCIPLINARY EXAMINATION AT THE SPECIALIZED LEARNING CENTER (NEA) OF FACULDADE DE MEDICINA DO ABC

Introdução

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by clinically significant and persistent deficits in communication and social interactions associated with restricted and repetitive patterns of behavior, interests and activities¹. ASD can be associated with several comorbidities, including Intellectual Disability, ADHD, anxiety, depression, epilepsy and sleep disorders ². In the context of ASD comorbidities, intellectual disability (ID) is among those whose presence is directly related to the level of support of patients, and its assessment is important from the point of view of functionality of each individual. According to data from the CDC³, 35.2% of ASD patients with cognitive examination data were classified as having ID. Overall, the proportions of this comorbidity in girls and boys were similar (35.6% and 35.1%, respectively).

Objetivo

Assessing the total prevalence of ID as a comorbidity of ASD and compare the prevalence of this comorbidity in male and female patients.

Métodos

Data from the medical records of a sample of patients who underwent a multidisciplinary examination at the Specialized Learning Center (NEA) of the Faculdade de Medicina do ABC (FMABC) were used. The sample consists of 1321 patients who underwent cognitive examination. We analyzed the prevalence data of patients diagnosed with ASD in the sample and, in these, ID as a comorbidity, as well as the proportion between male and female patients. Diagnoses made before the 2013 DSM-V, which included Pervasive Developmental Disorder and Asperger Syndrome, were discarded.

Resultados

The sample had 28 patients with ASD, 7 of whom had ID as a comorbidity (25%). In the group of girls (n=4) 1 had ID (25%) and in the group of boys (n=24) 6 had this comorbidity (25%).

Conclusões

The prevalence of ID as an ASD comorbidity in the sample presented was slightly lower than that observed in previous data in the literature. However, there were no significant differences in the proportions of this comorbidity between girls and boys, which corroborates the hypothesis that the prevalence of ID in patients with ASD is similar in both genders.

Palavras chave

Autism Spectrum Disorder ; intellectual disability

Referências (se houver)

1. AMERICAN PSYCHIATRIC ASSOCIATION. DSM-5: Manual diagnóstico e estatístico de transtornos mentais. 5. ed. Porto Alegre: Artmed, 2014.

2. Levy SE, Mandell DS, Schultz RT. Autism. The Lancet. 2009 Nov;374(9701):1627–38.

3. Maenner MJ, Shaw KA, Bakian AV, et al. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018. MMWR Surveill Summ 2021;70(No. SS-11):1–16

Declaração de conflito de interesses de TODOS os autores

Os autores declaram não haver conflitos de interesse.

Área

Transtornos neuropsiquiátricos e distúrbios de aprendizagem

Instituições

Faculdade de Medicina do ABC - São Paulo - Brasil

Autores

Kleiton Rodolfo Silveira Rufino, Rubens Wajnsztejn, Alessandra Bernardes Caturani Wajnsztejn, Keila Paula Pereira Chaves, Vanessa Ferreira Horta, Damaris Alcidia Gaester Fakler, Ketlyn Gil Garcia, Carina Cássia Zaneli, Sandra Ramos Gonçalves