Patrick Chauvel became an INSERM (Paris) researcher into the mechanisms of the epilepsies, after achieving his medical and scientific studies in Neurology and in Neuroscience.  At that time, he developed SEEG (Stereo-Electro-EncephaloGraphy) as a presurgical method in epilepsy surgery. His research work has been devoted to the pathophysiology of the epileptogenic zone, emergence of seizure clinical semiology, and cerebral cortex physiology. He has promoted the concept of epileptogenic network over the classical epileptic focus idea and opened new vistas in markers of the epileptogenic zone and semiology of focal epilepsies. Patrick Chauvel served as the Director of the SEEG Unit in Hospital Sainte-Anne in Paris, then Professor and Chairman of Neurology followed by Professor and Chairman of Clinical Neurophysiology and Director of the INSERM Institute of Systems Neuroscience in Marseille, configuring a new type of Epilepsy Unit including research.  Afterwards, he relocated to the Epilepsy Center of the Cleveland Clinic, where, as a Professor of as Professor of Neurology at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University promoted the development of presurgical investigation using SEEG in North America. In Brisbane, as Honorary Professor at the University of Queensland, he guided developing SEEG-based epilepsy surgery and related research program.